Ritocom Lopinavir And Ritonavir Tablets

  • Product Name : Ritocom Lopinavir And Ritonavir Tablets
  • Category : Anti HIV
  • Manufacturer Name : Hetero Healthcare
  • Trade Name : Ritocom
  • Available Dosage : 30 Tablets
  • Packing : Bottle
  • Pack Insert/Leaflet : 1 Pack/30 Tablets
  • Ingredients : Ritonavir, Lopinavir
  • Formulation : Tablet
  • Therapeutic use : anti-HIV medicines
  • Production Capacity : 100000

Description:-

Introduction to Ritocom Lopinavir And Ritonavir Tablets

Ritocom Lopinavir and Ritonavir Tablets is a combination antiretroviral medication used in the treatment of HIV-1 infection. This combination includes Lopinavir, a protease inhibitor, and Ritonavir, which enhances the effectiveness of Lopinavir by inhibiting its metabolism. Ritocom is a crucial component of antiretroviral therapy (ART) regimens aimed at managing HIV infection and preventing its progression to AIDS.


Uses of Ritocom Lopinavir And Ritonavir Tablets

Treating HIV-1 infection in adults and children

Used as part of combination antiretroviral therapy (ART)

Preventing the progression of HIV infection to AIDS


Benefits of Ritocom Lopinavir And Ritonavir Tablets

Potent Antiviral Activity: Effectively reduces viral load and increases CD4 cell counts.

Combination Therapy: Enhances the effectiveness of ART regimens by combining two protease inhibitors.

Resistance Management: Helps in managing drug resistance, a common issue in long-term HIV treatment.

Improved Quality of Life: Helps in maintaining immune function and overall health in HIV-infected individuals.


Mechanism of Action of Ritocom Lopinavir And Ritonavir Tablets

Lopinavir and Ritonavir work together to inhibit the HIV protease enzyme, which is essential for the maturation of infectious virus particles. Lopinavir binds to the active site of the protease enzyme, preventing it from cleaving the viral polyprotein precursors into functional proteins required for viral replication. Ritonavir acts primarily as a pharmacokinetic enhancer by inhibiting the cytochrome P450 3A4 enzyme, which metabolizes Lopinavir. This inhibition increases the plasma concentration of Lopinavir, thereby enhancing its antiviral efficacy. By preventing the replication of the virus, Ritocom Lopinavir and Ritonavir Tablets help reduce viral load and improve immune function in patients with HIV infection.