Welcome To Welox Pharma WHO-GMP | ISO 9001:2015
Translated into:
Welcome To Welox Pharma WHO-GMP | ISO 9001:2015
Introduction to Toppirome-S Cefpirome And Sulbactam Injection
Toppirome-S Cefpirome And Sulbactam Injection, offered by Lexaro Healthcare, combines Cefpirome and Sulbactam to deliver a robust treatment for severe bacterial infections. This formulation is designed to maximize the antibacterial efficacy of Cefpirome by combining it with Sulbactam, which inhibits beta-lactamase enzymes produced by resistant bacteria.
Uses of Toppirome-S Cefpirome And Sulbactam Injection
Toppirome-S is primarily used for:
Treating complicated intra-abdominal infections, including peritonitis and abscesses.
Managing hospital-acquired pneumonia and ventilator-associated pneumonia.
Treating complicated urinary tract infections caused by resistant bacteria.
Managing severe skin and soft tissue infections, including diabetic foot infections.
Treating bacterial septicemia and endocarditis.
Managing bone and joint infections, including osteomyelitis.
Benefits of Toppirome-S Cefpirome And Sulbactam Injection
Broad-Spectrum Antibiotic: Effective against a wide range of Gram-positive and Gram-negative bacteria, including multidrug-resistant strains.
Combination Therapy: Sulbactam enhances the efficacy of Cefpirome by inhibiting beta-lactamase enzymes, thereby overcoming bacterial resistance.
High Efficacy: Provides robust and rapid action against severe bacterial infections.
Reduced Resistance Risk: Combination therapy reduces the risk of developing antibiotic resistance.
Comprehensive Treatment: Suitable for treating a variety of serious infections, offering versatile therapeutic options.
Mechanism of Action of Toppirome-S Cefpirome And Sulbactam Injection
Cefpirome and Sulbactam, the active ingredients in Toppirome-S, work by:
Inhibiting Cell Wall Synthesis: Cefpirome binds to penicillin-binding proteins (PBPs) on bacterial cell walls, inhibiting the final step of peptidoglycan synthesis, which is essential for bacterial cell wall integrity. This leads to cell lysis and death of the bacteria.
Preventing Enzymatic Degradation: Sulbactam inhibits beta-lactamase enzymes produced by resistant bacteria, protecting Cefpirome from enzymatic degradation. This enhances the antibiotic activity of Cefpirome against beta-lactamase-producing organisms.
Broad-Spectrum Activity: Cefpirome is effective against a wide range of bacteria, including both aerobic and anaerobic, Gram-positive and Gram-negative organisms. This broad-spectrum activity makes it useful for treating mixed infections and severe infections where the causative organism is not immediately known.