Introduction to Artewel
Artewel (Artesunate Injection 60 mg) is a potent antimalarial drug used for the treatment of severe malaria, particularly Plasmodium falciparum infections. As a water-soluble artemisinin derivative, it exhibits rapid parasite clearance and significantly reduces malaria-related complications and mortality. It is recommended for hospitalized patients requiring immediate treatment.
Uses of Artewel
Severe malaria caused by Plasmodium falciparum
Cerebral malaria and multi-organ dysfunction due to malaria
Malaria in drug-resistant cases where oral therapy is ineffective
Initial treatment before switching to oral antimalarial therapy
Benefits of Artewel
Fast-acting with a rapid parasite clearance rate
Highly effective in severe and drug-resistant malaria cases
Lower risk of hypoglycemia compared to quinine therapy
WHO-recommended first-line therapy for severe malaria
Can be administered intravenously (IV) or intramuscularly (IM) for quick absorption
Mechanism of Action of Artewel
Artesunate, the active component of Artewel, generates reactive oxygen species (ROS) upon activation inside malarial parasites. This leads to parasite death by damaging their membranes and essential proteins. Its rapid antiparasitic effect makes it ideal for critical malaria cases, significantly reducing parasite burden within 24-48 hours.