Introduction to Ceftriaxone
Ceftriaxone is a broad-spectrum cephalosporin antibiotic effective in treating a wide range of bacterial infections. It is an essential medication in both therapeutic and preventive healthcare settings.
Uses of Ceftriaxone
Ceftriaxone is indicated for:
Treatment of bacterial infections in diverse anatomical sites
Prophylaxis against infections prior to surgical interventions
Management of severe infections, including pneumonia, meningitis, and sepsis
Benefits of Ceftriaxone
Broad-Spectrum Efficacy: Effective against a variety of gram-positive and gram-negative bacteria.
Prophylactic Use: Reduces the risk of postoperative infections when administered before surgery.
Established Safety Profile: Widely used in clinical practice with a proven history of safety and efficacy.
Mechanism of Action of Ceftriaxone
Ceftriaxone exerts its antibacterial effect by inhibiting bacterial cell wall synthesis. By binding to penicillin-binding proteins (PBPs), it disrupts the integrity of the bacterial cell wall, leading to cell lysis and death.