Gliclazide & Metformin Hydrochloride Tablets

  • Product Name : Gliclazide & Metformin Hydrochloride Tablets
  • Category : Tablet
  • Manufacturer Name : Panacea Biotec Ltd
  • Trade Name : Glizid-M
  • Available Dosage : 300 tablets
  • Packing : Strip
  • Pack Insert/Leaflet : 1 Pack/300 Tablets
  • Ingredients : Metformin Hydrochloride, Gliclazide
  • Formulation : Tablet
  • Therapeutic use : used in the treatment of type 2 diabetes mellitus (DM)
  • Production Capacity : 100000

Description:-

Introduction to Glizid-M Gliclazide & Metformin Hydrochloride Tablets

Glizid-M Tablets combine gliclazide, a sulfonylurea, and metformin, a biguanide, into one convenient dosage form. This combination therapy is designed to improve blood sugar control in individuals with type 2 diabetes by addressing different aspects of glucose metabolism.


Uses of Glizid-M Gliclazide & Metformin Hydrochloride Tablets

Type 2 Diabetes Management: Provides effective glycemic control in patients with type 2 diabetes when diet and exercise alone are insufficient.

Blood Glucose Regulation: Helps lower elevated blood glucose levels and maintain them within a target range.

Reduction of Insulin Resistance: Metformin improves insulin sensitivity, while gliclazide stimulates insulin secretion, offering a dual mechanism for glucose management.

Prevention of Diabetes-Related Complications: Effective control of blood sugar levels helps reduce the risk of complications such as neuropathy, nephropathy, and retinopathy.


Benefits of Glizid-M Gliclazide & Metformin Hydrochloride Tablets

Dual Mechanism of Action: Combines gliclazide's insulinotropic effect with metformin's insulin-sensitizing properties for comprehensive glucose control.

Convenient Combination Therapy: Simplifies treatment regimens by reducing the need for multiple medications.

Improved Glycemic Control: Helps achieve better blood sugar levels compared to single-agent therapy.

Reduced Risk of Hypoglycemia: Metformin reduces the risk of hypoglycemia commonly associated with sulfonylureas when used alone.

Weight Management: Metformin can help with weight control, which is beneficial for diabetes management.


Mechanism of Action of Glizid-M Gliclazide & Metformin Hydrochloride Tablets

Gliclazide:

Insulin Secretion Stimulation: Gliclazide stimulates beta cells in the pancreas to release more insulin, which helps lower blood glucose levels.

Inhibition of Gluconeogenesis: It reduces glucose production by the liver, contributing to lower blood sugar levels.

Metformin:

Increased Insulin Sensitivity: Metformin enhances the body's response to insulin, allowing for better glucose uptake by cells.

Decreased Hepatic Glucose Production: It reduces glucose production in the liver, which helps lower blood glucose levels.