Introduction to Glizid-M Gliclazide & Metformin Hydrochloride Tablets
Glizid-M Tablets combine gliclazide, a sulfonylurea, and metformin, a biguanide, into one convenient dosage form. This combination therapy is designed to improve blood sugar control in individuals with type 2 diabetes by addressing different aspects of glucose metabolism.
Uses of Glizid-M Gliclazide & Metformin Hydrochloride Tablets
Type 2 Diabetes Management: Provides effective glycemic control in patients with type 2 diabetes when diet and exercise alone are insufficient.
Blood Glucose Regulation: Helps lower elevated blood glucose levels and maintain them within a target range.
Reduction of Insulin Resistance: Metformin improves insulin sensitivity, while gliclazide stimulates insulin secretion, offering a dual mechanism for glucose management.
Prevention of Diabetes-Related Complications: Effective control of blood sugar levels helps reduce the risk of complications such as neuropathy, nephropathy, and retinopathy.
Benefits of Glizid-M Gliclazide & Metformin Hydrochloride Tablets
Dual Mechanism of Action: Combines gliclazide's insulinotropic effect with metformin's insulin-sensitizing properties for comprehensive glucose control.
Convenient Combination Therapy: Simplifies treatment regimens by reducing the need for multiple medications.
Improved Glycemic Control: Helps achieve better blood sugar levels compared to single-agent therapy.
Reduced Risk of Hypoglycemia: Metformin reduces the risk of hypoglycemia commonly associated with sulfonylureas when used alone.
Weight Management: Metformin can help with weight control, which is beneficial for diabetes management.
Mechanism of Action of Glizid-M Gliclazide & Metformin Hydrochloride Tablets
Gliclazide:
Insulin Secretion Stimulation: Gliclazide stimulates beta cells in the pancreas to release more insulin, which helps lower blood glucose levels.
Inhibition of Gluconeogenesis: It reduces glucose production by the liver, contributing to lower blood sugar levels.
Metformin:
Increased Insulin Sensitivity: Metformin enhances the body's response to insulin, allowing for better glucose uptake by cells.
Decreased Hepatic Glucose Production: It reduces glucose production in the liver, which helps lower blood glucose levels.