Introduction to Welzid 500
Welzid 500 (Pyrazinamide Tablets 500 mg) is an anti-tuberculosis medication used as part of combination therapy for active tuberculosis. It plays a crucial role in reducing bacterial load during the initial treatment phase.
Uses of Welzid 500
Used in combination with other anti-TB drugs to treat pulmonary and extrapulmonary tuberculosis.
Helps shorten the duration of TB therapy by accelerating bacterial clearance.
Benefits of Welzid 500
Effective against Mycobacterium tuberculosis in acidic environments.
Enhances the efficacy of standard TB regimens.
Helps prevent the development of drug-resistant TB strains.
Mechanism of Action of Welzid 500
Pyrazinamide is converted to its active form, pyrazinoic acid, which disrupts bacterial fatty acid synthesis, leading to cell membrane damage and bacterial death. It is most effective in acidic pH environments found within macrophages, where tuberculosis bacteria reside.